Caffeine: a beneficial psychoactive substance?

Caffeine belongs to stimulants of central nervous system and at the same time demonstrates a wide range of beneficial effects. Among other properties, caffeine has the ability to prevent and mitigate the symptoms of Alzheimer's disease and other forms of neurodegenerative impairment, obesity and type 2 diabetes. Contrary to traditional beliefs, caffeine in many cases does not exacerbate manifestations of hypertension and other cardiovascular diseases, but has a neutral or positive effect on blood pressure and other cardiac functions. It must be taken into account that, along with the beneficial effects of caffeine, especially in great amounts, the substance can cause unwanted and dangerous effects. Despite the dramatic number of accumulated facts about the health benefits of caffeine, in vitro and animal studies are still prevailing over controlled clinical trials, and the elaboration of recommendations for the clinical use of caffeine requires additional studies to confirm the efficacy and safety of this treatment approach.

Key words: coffee, caffeine, dementia, Alzheimer's disease, diabetes mellitus, overweight, obesity, cardiovascular diseases, apnea in preterm infants, sleep deprivation, neurogenesis.

For citation: Sivolap Yu.P., Damulin I.V. Caffeine: a beneficial psychoactive substance? Vopr. dietol. (Nutrition). 2017; 7(1): 42–46 (In Russian).
DOI: 10.20953/2224-5448-2017-1-42-46