Clinico-economic analysis of the effectiveness of correction of the nutritional status in patients with compensated and subcompensated forms of esophageal achalasia

The objective. Optimization of preoperational nutritional support of patients with compensated and subcompensated forms of esophageal achalasia (EA).

Patients and methods. The examination included 109 patients (45 males, 64 females) with early forms of EA. Depending on the severity of organic and functional changes of the esophagus, the patients were divided into two groups: group 1 – compensated form (n = 36) and group 2 – subcompensated form (n = 73). All the patients received a light diet (LD). Correction of the nutritional status was performed in 32 patients of group 2 (group 2а) with the sipping formula Nutridrink (Nutricia, Netherlands) in the dose 200 ml 2–3 times daily after meals for 14 days. The other patients of group 2 (n = 41) comprised the reference group (2b). In group 1 patients, no correction of the nutritional status was performed.

Results. In group 2a patients, the values of total protein, albumin and total lymphocyte count significantly increased as compared with group 2b patients. Overall costs of management of patients with EA who do not receive preoperational nutritional support exceed 1.3-fold the costs for management of patients with EA who additionally received the sipping formula for 14 days before surgery.

Conclusion. The obtained evidence substantiate the clinical and economic expediency of administering adequate nutritional support with sipping formulas in patients with EA at the stage of preoperational preparation.

Key words: esophageal achalasia, clinico-economic efficacy, nutritional support, nutritional status

Яндекс.Метрика