Influence of an antiaterogenic diet enriched with phytosterins and amaranth oil on the clinico-biochemical indices in patients with cardiovascular disorders
The work was performed with the objective to assess the influence of an antiaterogenic diet enriched with vegetative food components having hypolipidemic effect (phytosterins and amaranth oil) on clinico-biochemical values in patients with cardiovascular diseases. The examination included 85 patients with ischaemic heart disease and hypertensive disease grade I–II with obesity and hyperlipoproteidemia, who for a 3-week period of study received one of the three variants of diet therapy: a variant of standard diet with reduced calorie value- a variant of standard diet enriched with phytosterins, and a variant of standard diet in which 20 g of sunflower oil were substituted with the same quantity of a mixture of amaranth and corn oils. As was found, enrichment of an antiaterogenic diet with phytosterins and amaranth oil promoted improvement of the clinical status and the anthropometric values of the patients, a noticeable improvement of the indices of central hemodyna mics. Thus, in the process of treatment the levels of systolic BP decreased by 8.6. 17 (p <- 0.01) and 8.0%, diastolic BP – by 8.6. 12 (p <- 0.05) and 6.4%, respectively. Enrichment of diet with vegetative food components having a hypolipidemic effect contributed to a statistical y significant decrease of the levels of total cholesterol in the group that received the standard diet variant enriched with phytosterins by 20% (p <- 0.001), in the group that received amaranth oil – by 19% (p <- 0.05), and in the reference group by 11% (p <- 0.05). Decrease of LDL cholesterol levels amounted to 24% (p <- 0.01), 23 and 15% (p <- 0.05), respectively. Therefore, the study has showed that the use of phytosterins and amaranth oil for therapeutic and preventive purposes has good perspectives.
phytosterins, diet therapy, ischaemic heart disease, hypertensive disease, antiaterogenic diet