Gynecology, Obstetrics and Perinatology

Complications of pregnancy, childbirth and the postpartum period in women with hypothalamic obesity in adolescence

Objective. To study the features of the course of pregnancy and to identify the main risk factors for the development of obstetric complications in women with hypothalamic dysfunction (HD) and obesity in medical history.
Patients and methods. In this study, 72 women of reproductive age with HD and metabolic disorders in medical history were examined. 
Results. For women with hypothalamic dysfunction and metabolic disorders in medical history, the following pregnancy complications were identified: threatened miscarriage in 16.7%, spontaneous abortion in 11.1%, pre-eclampsia in 20.3%, edema with proteinuria, gestational diabetes mellitus, intrauterine hypoxia and anemia – 17.2% each, threatened preterm labor in 9.4%, labor disorders in 23.4%; every second postpartum woman had hypogalactia.
Conclusion. The risk group for early pregnancy loss should include women with HD and metabolic disorders in medical history who had secondary amenorrhea. The risk group for the development of gestational diabetes mellitus should include women with HD and metabolic disorders in medical history who plan infertility treatment by means of assisted reproductive technologies. 

Key words: obstetric complications, pregnancy, hypothalamic dysfunction, obesity, puberty, risk factors
For citation: Leshchenko O.Ya., Zhukovets I.V. Complications of pregnancy, childbirth and the postpartum period in women with hypothalamic obesity in adolescence. Vopr. ginekol. akus. perinatol. (Gynecology, Obstetrics and Perinatology). 2021; 20(3): 28–36. (In Russian). DOI: 10.20953/1726-1678-2021-3-28-36

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