Gynecology, Obstetrics and Perinatology

Fibrolamellar hepatocellular carcinoma and pregnancy. Tactics of treatment

Hepatocellular carcinoma (HCC) is rarely diagnosed during pregnancy, its fibrolamellar variant (FHCC) is a specific form that is more often diagnosed in young women and is rarely associated with cirrhosis or chronic infection with hepatitis B or C viruses. Making a diagnosis at early stages is complicated by the fact that the α-fetoprotein (AFP) level is usually not enhanced, and symptoms develop only at advanced stages of disease. A clinical case of FHCC in a 27-year-old woman is presented, diagnosed at the 30th week of pregnancy after persistent dragging and spastic pains in the epigastric region. US detected a
tumour with sizes 110 × 81 × 89 mm and foci in the lungs. Variants of treating such patients depending on tumour characteristics, pregnancy period and family preferences are discussed.

Key words: pregnancy, hepatocellular carcinoma, tactics of managements, fibrolamellar variant.

For citation: Ignatko I.V., Afanas’eva N.V., Snegovoy А.V., Ryabchikov D.А., Dudina I.A., Golubenko E.O., Matsneva I.A. Fibrolamellar hepatocellular carcinoma and pregnancy. Tactics of treatment. Vopr. ginekol. akus. perinatol. (Gynecology, Obstetrics and Perina-tology). 2018; 17(3): 101–106.
(In Russian).
DOI: 10.20953/1726-1678-2018-3-101-106