Gynecology, Obstetrics and Perinatology

Thrombotic microangiopathy as a manifestation of severe preeclampsia and HELLP syndrome

The article presents a clinical case of a patient with severe preeclampsia, HELLP-syndrome, manifested by thrombotic microangiopathy. Thrombotic microangiopathy (TMA) is a clinical-morphological syndrome with an underlying injury of the endothelium of microcirculatory vessels associated with various causes but manifested by similar clinical symptoms and histological signs. At present, TMA is regarded as an inalienable part of the pathogenesis of severe obstetric complications – preeclampsia and HELLP syndrome. The article presents a clinical picture, differential diagnostic search, and management of the patient in the settings of a Moscow multi-field hospital.

Key words: haemolytic-uraemic syndrome, preeclampsia, thrombotic microangiopathy, thrombotic thrombocytopenic purpura, HELLP syndrome.

For citation: Strizhakov A.N., Timokhina E.V., Ignatko I.V., Protsenko D.N., Troshchanskiy D.V., Afanas’eva N.V., Ignatenko O.V., Ibragimova S.М. Thrombotic microangiopathy as a manifestation of severe preeclampsia and HELLP syndrome. Vopr. ginekol. akus. perinatol. (Gynecology, Obstetrics and Perinatology). 2017; 16(6): 89–92. (In Russian).
DOI: 10.20953/1726-1678-2017-6-89-92

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