A comparative assessment of the incidence and structure of preterm labour in women after in vitro fertilisation with donor and own eggs
Patients and methods. We analysed the course of pregnancy, labour and perinatal outcomes in 886 women. In 233 women, pregnancy occurred after IVF with the use of donor eggs (IVF-DE), in 236 patients as a result of the «surrogate motherhood» programme (IVF-SM), in 211 women pregnancy resulted from IVF with own eggs (IVF-OE) and in 206 women – spontaneously (SP). The study included only women, whose pregnancy ended with childbirth.
Results. Pregnancy after IVF is associated with a high incidence of preterm labour, especially in case of using donor eggs and in surrogate mothers. The highest incidence of induced preterm labour was noted in the IVF-DE group. Neonatal mortality was only in IVF groups and only after preterm labour: in two cases of very early preterm labour (24 and 27 wks of gestation), and in one case of early preterm labour (29 wks of gestation).
Conclusion. Prevention of preterm labour in induced pregnancy should be, first of all, aimed at avoiding a multiple pregnancy. Also, doctors should seek prevention of gestational complications that are the cause of induced preterm labour.
Key words: egg donation, preterm labour, surrogate motherhood, IVF.
For citation: Zhukova E.V., Trifonova N.S., Aleksandrov L.S., Ishchenko A.I., Borisova N.I., Nikonov A.P., Grineva A.M. A comparative assessment of the incidence and structure of preterm labour in women after in vitro fertilisation with donor and own eggs. Vopr. ginekol. akus. perinatol. (Gynecology, Obstetrics and Perinatology). 2017; 16(3): 24–30. (In Russian).