Gynecology, Obstetrics and Perinatology

The course of pregnancy, labour and perinatal outcomes in surrogate mothers

The objective. To study the incidence and structure of obstetric complications and perinatal outcomes in surrogate mothers. 

Patients and methods. We have analysed the course of pregnancies, labours and perinatal outcomes in 213 surrogate mothers and in 193 secundiparas, in whom pregnancy occurred after IVF with own eggs (control group). The study included only women, whose pregnancy ended with childbirth.

Results. The course of pregnancy, labour and the postpartum period in surrogate mothers is associated with a high risk of such complications as preeclampsia (8.5%), premature separation of the normally implanted placenta (4.7%), hypotonic bleeding (6.1%), placenta adhaerens (6.6%), retained placenta (6.6%), premature birth (23.0%) (p < 0.05). The course of this pregnancy in more than a half of surrogate mothers was accompanied by threatened miscarriage.

Conclusion. In surrogate mothers, as compared with the population, an increased incidence of complications of pregnancy, labour and the postpartum period is noted. This might be conditioned by response of a woman’s immune system to transfer of a fully allogeneic embryo.

Key words: hypotonic bleeding, egg donation, perinatal outcomes, placenta adhaerens, preterm labour, preeclampsia, surrogate motherhood.

For citation: Trifonova N.S., Zhukova E.V., Aleksandrov L.S., Nikonov A.P., Ishchenko A.I., Borisova N.I., Grineva A.M., Soboleva V.V. The course of pregnancy, labour and perinatal outcomes in surrogate mothers. Vopr. ginekol. akus. perinatol. (Gynecology, Obstetrics and Perinatology). 2017; 16(3): 6–13. (In Russian).
DOI: 10.20953/1726-1678-2017-3-6-13

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