Gynecology, Obstetrics and Perinatology

The course of infectious process in pregnant women carrying herpes virus with non-differentiated forms of connective tissue dysplasia

In pregnant women carrying herpes virus with non-differentiated connective tissue dysplasia (NFCTS), disorder of cell-mediated immunity was found, which was characterized by relative insufficiency of Т-lymphocytes (CD3), with deficiency of subpopulation of Т-helpers (CD4) and predominance of lymphocyte subpopulations participating in humoral immunity – CD16 (NK-cells, granulocytes, macrophages) and CD20 (B-lymphocytes). Disorders in the system of cell-mediated immunity in pregnant carriers of GHV with NFCTS increased a risk for realization of infection, which was indirectly manifested by inflammatory lesion of the  placenta with formation of secondary placental insufficiency and worse perinatal outcomes.


Яндекс.Метрика