Efficacy and acceptability of combined oral contraceptives in a prolonged regimen
The article presents the results of studying the efficacy and acceptability of using the combined oral contraceptive (COC) Marvelon in a prolonged regimen, and also additional non-contraceptive benefits of a prolonged scheme of taking the COC. The prolonged regimen was found to be effective and acceptable in patients of reproductive age who needed effective contraception. Evidence about additional non-contraceptive benefits of a prolonged regimen in patients with symptoms of PMS, primary dysmenorrhea, and hyperpolymenorrhea was received. The data obtained in the course of the study were indicative of the absence of a negative effect of the prolonged scheme on both the general state of the patients and on the indices of arterial blood pressure and body weight. Side effects in the form of intermenstrual blood-tinged discharge occurred mainly in the first three months of taking the COC and did not require administration of additional therapy. The results of the study permit to consider a prolonged regimen of intake of Marvelon to be an effective and safe contraception method that has a number of noncontraceptive benefits.